杜康，男，1990年11月生人，于2018年6月獲中國(guó)科學(xué)院水生生物研究所水生生物學(xué)專業(yè)的博士學(xué)位；2018年至2024年間先后于德國(guó)維爾茨堡大學(xué)、美國(guó)德克薩斯州立大學(xué)大學(xué)從事博士后研究工作；現(xiàn)任中國(guó)水產(chǎn)科學(xué)研究院黃海水產(chǎn)研究所研究員、碩士生導(dǎo)師、博士后合作導(dǎo)師；研究方向?yàn)椋呼~(yú)類性別決定的遺傳基礎(chǔ)和演化機(jī)制。
主持國(guó)家自然科學(xué)基金優(yōu)秀青年科學(xué)基金項(xiàng)目（海外）；以第一作者（含并列）、共同通訊作者在Nature、Nature Ecology & Evolution、Nature Communications、Genome Research等雜志上發(fā)表多篇論文。
聯(lián)系電話：0532-85831605
通訊地址：山東省青島市南京路106號(hào)中國(guó)水產(chǎn)科學(xué)研究院黃海水產(chǎn)研究所
郵政編碼：266071
E-mail：dukang@ysfri.ac.cn
微信：UFOalone
主要研究?jī)?nèi)容、研究方向
物競(jìng)天擇，適者生存；然而，若無(wú)法繁衍，生存便失去了演化意義。有性生殖作為主要的繁衍方式，其起源十分古老，但各物種的性別決定機(jī)制卻并不保守，展現(xiàn)出高度的可塑性和多樣性，其背后的遺傳機(jī)制和演化意義尚不得知。
本人以魚(yú)類為研究模型，從系統(tǒng)發(fā)育學(xué)出發(fā)，調(diào)查性染色體的起源與演化模式；結(jié)合種群基因組學(xué)手段，追蹤性別決定基因與性染色體的演變過(guò)程；同時(shí)引入單細(xì)胞測(cè)序與空間轉(zhuǎn)錄組等技術(shù)，探究性別決定系統(tǒng)的遺傳機(jī)制和演化規(guī)律。
研究成果將有利于演化理論的推進(jìn)和水產(chǎn)性控育種技術(shù)的發(fā)展。
代表性論著（*為共同一作，#為共同通訊）
1)Kang Du, Oliver Deusch, Ilja Bezrukov, Christa Lanz, Yann Guiguen, Margarete Hoffmann, Anette Habring, Detlef Weigel, Manfred Schartl & Christine Dreyer, “Identification of the male-specific region on the guppy Y Chromosome from a haplotype-resolved assembly.” Genome Research (2025)
2)Kang Du, Yuan Lu, Mateo Garcia-Olazabal, Ronald B Walter, Wesley C Warren, Tristram Dodge, Molly Schumer, Hyun Park, Axel Meyer & Manfred Schartl, “Phylogenomics analyses of all species of Swordtails (Genus Xiphophorus ) highlights hybridization precedes speciation.” Nature Communications (2024)
3)Min-Rui-Xuan Xu*, Zhen-Yang Liao*, Jordan R Brock*, Kang Du*, Guo-Yin Li, Zhi-Qiang Chen, Ying-Hao Wang, Zhong-Nan Gao, Gaurav Agarwal, Kevin H-C Wei, Feng Shao, Shuai Pang, Adrian E Platts, Jozefien van de Velde, Hong-Min Lin, Scott J Teresi, Kevin Bird, Chad E Niederhuth, Jin-Gen Xu, Guo-Hua Yu, Jian-Yuan Yang, Si-Fa Dai, Andrew Nelson, Ingo Braasch, Xiao-Gu Zhang, Manfred Schartl, Patrick P Edger, Min-Jin Han & Hua-Hao Zhang, “Maternal dominance contributes to subgenome differentiation in allopolyploid fishes.” Nature Communications (2023)
4)Heiner Kuhl*, Kang Du*, Manfred Schartl, Luká? Kalous, Matthias St?ck & Dunja K. Lamatsch, “Equilibrated evolution of the mixed auto-/allopolyploid haplotype-resolved genome of the invasive hexaploid Prussian carp.” Nature Communications (2022)
5)Kang Du#, Martin Pippel, Susanne Kneitz, Romain Feron, Irene da Cruz, Sylke Winkler, Brigitta Wilde, Edgar G Avila Luna, Gene Myers, Yann Guiguen, Constantino Macias Garcia & Manfred Schartl#, “Genome biology of the Darkedged Splitfin, Girardinichthys multiradiatus, and the evolution of sex chromosomes and placentation.” Genome research (2022)
6)Axel Meyer*, Siegfried Schloissnig*, Paolo Franchini*, Kang Du*, Joost Woltering*, Iker Irisarri, Wai Yee Wong, Sergej Nowoshilow, Susanne Kneitz, Akane Kawaguchi, Andrej Fabrizius, Peiwen Xiong, Corentin Dechaud, Herman Spaink, Jean-Nicolas Volff, Oleg Simakov, Thorsten Burmester, Elly M. Tanaka & Manfred Schartl. “Giant lungfish genome elucidates the conquest of land by vertebrates.” Nature. (2021)
7)Kang Du, Matthias St?ck, Susanne Kneitz, Christophe Klopp, Joost Woltering, Mateus Adolfi, Romain Feron, Dmitry Prokopov, Alexey Makunin, Ilya Kichigin, Cornelia Schmidt, Petra Fischer, Heiner Kuhl, Sven Wuertz, J?rn Gessner, Werner Kloas, Cedric Cabau, Carole Iampietro, Hugues Parrinello, Chad Tomlinson, Laurent Journot, John Postlethwait, Ingo Braasch, Vladimir Trifonov, Wesley C Warren, Axel Meyer, Yann Guiguen & Manfred Schartl. “An ancient whole genome duplication in a living fossil: the sterlet sturgeon genome sequence and the mechanisms of segmental rediploidization.” Nature Ecology & Evolution (2020)
