
陳亞東,男,19881013出生于山東泰安。助理研究員,于2014.7畢業于大連海洋大學水產與生命學院生物化學與分子生物學專業畢業。
研究方向為海洋生物分子生物學,涉及海洋生物免疫,微生物活性物質,魚類性別鑒定等相關研究,主要進行基因資源挖掘,分子機制闡述和基因功能分析,高利用價值基因產物應用等。
迄今為止,已在Dev Comp Immunol、Fish Shellfish Immunol等刊物上發表論文20多篇,其中第一作者5篇,以第二完成人獲授權發明專利1項。作為科研骨干參加了863課題“魚類功能基因的研究開發” 2012AA10A401-4);國家自然基金課題“半滑舌鰨microRNA表達譜構建與免疫相關性分析” (31172439);國家自然基金面上項目“半滑舌鰨補體信號通路及抗菌免疫防御機理(31572644)”。另外參加了國家自然科學基金重點項目、十二五863項目等10余項。
論文:1.Yadong Chen, Yongtao Xia, Changwei Shao, Lei Han, Xuejie Chen, Mengjun Yu, Zhenxia Sha, Discovery and identification of candidate sex-related genes based on transcriptome sequencing of Russian sturgeon (Acipenser gueldenstaedtii) gonads. Physiological Genomics, 2016, 48(7): 464~476.
2.Yadong Chen,Yaqing Chang, Xiuli Wang, Xuemei Qiu, Yang Liu. De novo assembly and analysis of tissue-specific transcriptomes revealed the tissue-specific genes and profile of immunity fromStrongylocentrotus intermedius. Fish and Shellfish Immunology, 2015, 46(2): 723-736.
3.Yadong Chen, Shuhong Zhou, Zhiqiang Jiang, Xiuli Wang, Yang Liu. Chemokine receptor CXCR3 in turbot (Scophthalmus maximus): cloning,
characterization and its responses to lipopolysaccharide. Fish physiology and biochemistry, 2016, 42(2): 659-671.
4.Yadong Chen, Zhenxia Sha, Shimei Wu, Songlin Chen, Yan Zeng, Does the different domain in sghC1q protein fromCynoglossus semilaevisperform functions independent? Gene Reports, 2017, 7: 59~63.
5.陳亞東,劉曉飛,常亞青,王秀麗,劉洋.蝦夷馬糞海膽NLR家族基因片段的克隆及表達特征分析.大連海洋大學學報, 2014, 29(4): 336-341.中文核心期刊
6. Liang Meng, Wenteng Xu,Yadong Chen#, Min Wei, Zhong-kai Cui, Yang Liu, Hua Guo, Xi Gan, Jiajie Zhu, Lin na Wang, Songlin Chen. pik3r3b, a novel immune-related gene in Nile tilapia (Oreochromis niloticus): Identification, expression and analysis of antibacterial activity[J]. Fish & shellfish immunology, 2019, 87: 705-713.
7.Kun-ming Li, Ming Li, Na Wang,Ya-dong Chen, Xi-wen Xu, Wen-teng Xu, Lei Wang, Song-lin Chen. Genome-wide identification, characterization, and expression analysis of the TRAF gene family in Chinese tongue sole (Cynoglossus semilaevis),[J]. Fish & shellfish immunology, 2019.doi.org/10.1016/j.fsi.2019.11.029.
8.Lin Huang, Li Bai,Yadong Chen, Qian Wang, Zhenxia Sha,Identification, expression profile and analysis of the antimicrobial activity of collectin 11 (CL-11, CL-K1), a novel complement-associated pattern recognition molecule, in half-smooth tongue sole (Cynoglossus semilaevis),Fish & Shellfish Immunology,2019,95, 679-687
9. Guang Yang, Yunji Xiu,Yadong Chen, Li Bai, Zhenxia Sha. Identification and expression of complement component C8α, C8β and C8γ gene in half-smooth tongue sole (Cynoglossus semilaevis) and C8α recombinant protein antibacterial activity analysis. Fish & shellfish immunology, 2018, 72. 658-699.
10.Zhenxia Sha, Linqing Wang, Luming Sun,Yadong Chen, Yuan Zheng, Mei Xin, Chen Li, Songlin Chen. Isolation and characterization of monocyte/macrophage from peripheral blood of half smooth tongue sole (Cynoglossus semilaevis). Fish & Shellfish Immunology, 2017, 65: 256-266.
11. Hui Yan,Yadong Chen, Shun Zhou, Chao Li, Guangye Gong, Xuejie Chen, Tianzi Wang, Songlin Chen, Zhenxia Sha. Expression Profile Analysis of miR-221 and miR-222 in Different Tissues and Head Kidney Cells ofCynoglossus semilaevis,Following Pathogen Infection, Marine Biotechnology, 2016,
18(1):37~48
12. Xuejie Chen,Yadong Chen, Mengjun Yu, Zhenxia Sha, Xiujuan Shan. The complete mitochondrial genome of theAzuma emmnion(Perciformes: Pholidae). Mitochondrial DNA Part A, 2017, 28(1): 77-78.
13. Jinsong Xiang, Xihong Li,Yadong Chen, Yang Lu, Mengjun Yu, Xuejie Chen, Wenting Zhang, Yan Zeng, Luming Sun, Songlin Chen, Zhenxia Sha. Complement factor I from flatfish half-smooth tongue (Cynoglossus semilaevis) exhibited anti-microbial activities. Developmental and Comparative Immunology, 2015, 53(1).199-209.
14.Yan Zeng, Jinsong Xiang, Yang Lu,Yadong Chen, Tianzi Wang, Guangye Gong, Lei Wang, Xihong Li, Songlin Chen, Zhenxia Sha. sghC1q, a novel C1q family member from half-smooth tongue sole (Cynoglossus semilaevis): Identification, expression and analysis of antibacterial and antiviral activities. Developmental and Comparative Immunology, 2015, 48.151-163.
15. Xiang Zhang, Shaolin Wang, Songlin Chen,Yadong Chen, Yang Liu, Changwei Shao, Qilong Wang, Yang Lu, Guangye Gong, Shaoxiong Ding, Zhenxia Sha. Transcriptome analysis revealed changes of multiple genes involved in immunity inCynoglossus semilaevisduringVibrio anguillaruminfection. Fish and Shellfish Immunology, 2015, 43(1):209-218.