
翟倩倩,女,1984年7月生人,于2013年7月獲北京協和醫學院微生物與生化藥學專業博士學位,現任中國水產科學研究院黃海水產研究所副研究員,碩士生導師。主要從事水產藥理學及健康養殖等方面的研究,主持國家自然科學基金、山東省自然科學基金、中國水產科學研究院基本科研業務費重點項目等科研項目6項,作為骨干參與國家現代農業產業技術體系、國家自然科學基金面上項目、國家重點研發計劃子課題等項目10余項;發表研究論文28篇(SCI收錄20篇)、以第一發明人授權國家發明專利4項、參編專著2部、研究成果獲中國水產學會范蠡科學技術獎一等獎(2019,16/20)、中國水產科學研究院科學技術獎二等獎,2021,12/15);2022年入選中國水產科學研究院“水科英才”培育計劃拔尖人才。
聯系電話,0532-85826690
通訊地址:山東省青島市南京路106號中國水產科學研究院黃海水產研究所
郵政編碼:266071
E-mail:zhaiqq@m.energicube.com
主要研究內容、研究方向
主要進行水產病原菌耐藥性、水產藥物代謝動力學、藥效學評價和藥物安全使用技術等研究,在水產病原菌耐藥性評估及耐藥機制研究、中西藥聯用藥效和安全性評價、海水養殖動物ABC轉運蛋白的功能和調控機制、常用水產藥物代謝動力學、水產動物生理藥動學模型等方面開展了深入研究。
研究方向:1)水產病原菌耐藥性研究;2)水產藥物藥效學;3)水產藥物代謝動力學及藥物殘留預測。
代表性論著(10篇以內)
1. Zhai QQ, Chang ZQ, Li JT, Li J. Effects of combined florfenicol and chlorogenic acid to treat acute hepatopancreatic necrosis disease in Litopenaeus vannamei caused by Vibrio parahaemolyticus. Aquaculture, 2022, 547: 737462.
2. Zhai QQ, Chang ZQ, Li JT, Li J. Protective Effects of Combined Utilization of Quercetin and Florfenicol on Acute Hepatopancreatic Necrosis Syndrome Infected Litopenaeus vannamei. Antibiotics, 2022, 11(12): 1784.
3. Zhai QQ, Xu Y, Li CP, Feng YY, Cui YT, Ma L, Li J. Inhibition of breast cancer resistance protein (BCRP) by Ko143 can affect pharmacokinetics of enrofloxacin in Exopalaemon carinicauda. Journal of Ocean University of China, 2020, 19(5): 1116-1124.
4. Zhai QQ, Li J. Effectiveness of traditional Chinese herbal medicine, San-Huang-San, in combination with enrofloxacin to treat AHPND-causing strain of Vibrio parahaemolyticus in fection in Litopenaeus vannamei. Fish and Shellfish Immunology, 2019, 87: 360-370.
5. Zhai QQ, Li J, Feng YY, Ge QQ. Evaluation of combination effects of Astragalus polysaccharides and florfenicol against acute hepatopancreatic necrosis disease-causing strain of Vibrio parahaemolyticus in Litopenaeus vannamei. Fish and Shellfish Immunology, 2019, 86: 374-383.
6. Zhai QQ, Li J, Chang ZQ. cDNA cloning, characterization and expression analysis of ATP-binding cassette transmembrane transporter in Exopalaemon carinicauda. Aquaculture Research, 2017, 48(8): 4143-4154.
7. Zhai QQ, Pang J, Li GQ, et al. Preclinical pharmacokinetic analysis of (E)-Methyl-4-aryl-4-oxabut-2-enoate, a novel SerThr protein kinase PknB inhibitor, in rats. Acta Poloniae Pharmaceutica. 2017, 74(1): 299-307.
8. Zhai QQ, Pang J, Li GQ, et al. 2015-Validated LC-MS/MS method for determination of YH-8, a novel PKnB inhibitor, in rat plasma and its application to pharmacokinetic study. Acta Pharmaceutica Sinica B. 2015, 5(5): 467-472.
9. Feng YY, Zhai QQ, Wang JJ, Li JT, Li J. Comparison of florfenicol pharmacokinetics in Exopalaemon carinicauda at different temperatures and administration routes. 2019, 42: 230-238.
10.翟倩倩,李健. 恩諾沙星對脊尾白蝦APND、ECOD和GST活性的影響. 海洋科學. 2017, 41(2): 53-60.